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Distance Measurements on a Dual-labeled TOAC AChR M2δ Peptide in Mechanically Aligned DMPC Bilayers via Dipolar Broadening CW-EPR Spectroscopy

A membrane alignment technique has been used to measure the distance between two TOAC nitroxide spin labels on the membrane-spanning M2δ, peptide of the nicotinic acetylcholine receptor (AChR), via CW-EPR spectroscopy. The TOAC-labeled M2δ peptides were mechanically aligned using DMPC lipids on a pl...

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Detalhes bibliográficos
Main Authors: Ghimire, Harishchandra, Hustedt, Eric J., Sahu, Indra D., Inbaraj, Johnson J., McCarrick, Robert, Mayo, Daniel J., Benedikt, Monica R., Lee, Ryan T., Grosser, Stuart M., Lorigan, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322368/
https://ncbi.nlm.nih.gov/pubmed/22379959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp212272d
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