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Wld(S )but not Nmnat1 protects dopaminergic neurites from MPP(+ )neurotoxicity

BACKGROUND: The Wld(S )mouse mutant ("Wallerian degeneration-slow") delays axonal degeneration in a variety of disorders including in vivo models of Parkinson's disease. The mechanisms underlying Wld(S )-mediated axonal protection are unclear, although many studies have attributed Wld...

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Autors principals: Antenor-Dorsey, Jo Ann V, O'Malley, Karen L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322348/
https://ncbi.nlm.nih.gov/pubmed/22315973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-5
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