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Deletion of human JK segments by site-specific recombination recognizing the conserved nonamer and heptamer sequences.

Mapping and partial sequencing of the productive K chain genomic DNA of FK-001 demonstrated a 1.8-kb deletion including the JK2, JK3, JK4, and JK5 segments. This deletion occurred between the heptamer recombination signal sequence of the JK2 segment and the heptamer-like sequence located 1.8 kb down...

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Udgivet i:Nucleic Acids Res
Principais autores: Nakatani, T, Horigome, K, Nomura, N, Kondo, T, Ohtsuka, H, Noguchi, H, Honjo, T
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1990
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332233/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5529
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