Chemical synthesis of biologically active oligoribonucleotides using beta-cyanoethyl protected ribonucleoside phosphoramidites.

The preparation of fully protected diisopropylamino-beta-cyanoethyl ribonucleoside phosphoramidites with regioisomeric purity greater than 99.95% is described. It is demonstrated that the combination of standard DNA protecting groups, 5'-O-DMT, N-Bz (Ade and Cyt), N-iBu (Gua), beta-cyanoethyl for ph...

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Argitaratua izan da:	Nucleic Acids Res
Egile Nagusiak:	Scaringe, S A, Francklyn, C, Usman, N
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Oxford University Press 1990
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332221/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5433
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