Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models

BACKGROUND: Hypoxic tumor cells can reduce the efficacy of radiation. Antiangiogenic therapy may transiently “normalize” the tumor vasculature to make it more efficient for oxygen delivery. The aim of this study is to investigate whether the recombinant human endostatin (endostar) can create a “vasc...

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Detalhes bibliográficos
Main Authors: Peng, Fang, Xu, Zumin, Wang, Jin, Chen, Yuanyuan, Li, Qiang, Zuo, Yufang, Chen, Jing, Hu, Xiao, Zhou, Qichao, Wang, Yan, Ma, Honglian, Bao, Yong, Chen, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322143/
https://ncbi.nlm.nih.gov/pubmed/22496834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034646
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