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Mixed chimerism and split tolerance: Mechanisms and clinical correlations

Establishing hematopoietic mixed chimerism can lead to donor-specific tolerance to transplanted organs and may eliminate the need for long-term immunosuppressive therapy, while also preventing chronic rejection. In this review, we discuss central and peripheral mechanisms of chimerism induced tolera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Al-Adra, David P., Anderson, Colin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321885/
https://ncbi.nlm.nih.gov/pubmed/22509425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chim.2.4.19017
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