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Human telomere disease due to disruption of the CCAAT box of the TERC promoter
Mutations in the coding region of telomerase complex genes can result in accelerated telomere attrition and human disease. Manifestations of telomere disease include the bone marrow failure syndromes dyskeratosis congenita and aplastic anemia, acute myeloid leukemia, liver cirrhosis, and pulmonary f...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321867/ https://ncbi.nlm.nih.gov/pubmed/22323451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-383182 |
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