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Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells
Androgens have been used in the treatment of bone marrow failure syndromes without a clear understanding of their mechanism of action. Blood counts of patients with dyskeratosis congenita or aplastic anemia with mutations in telomerase genes can improve with androgen therapy. Here we observed that e...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745844/ https://ncbi.nlm.nih.gov/pubmed/19561322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-178871 |
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