Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain

Noninvasive intranasal drug administration has been noted to allow direct delivery of drugs to the brain. In the present study, the therapeutic efficacy of intranasal small interfering RNA (siRNA) delivery was investigated in the postischemic rat brain. Fluorescein isothiocyanate (FITC)-labeled cont...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Il-Doo, Shin, Joo-Hyun, Kim, Seung-Woo, Choi, Sunghyun, Ahn, Junseong, Han, Pyung-Lim, Park, Jong-Sang, Lee, Ja-Kyeong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321593/
https://ncbi.nlm.nih.gov/pubmed/22252450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.291
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