Diurnal Fluctuation in Histidine Decarboxylase Expression, the Rate Limiting Enzyme for Histamine Production, and Its Disorder in Neurodegenerative Diseases

STUDY OBJECTIVES: Neuronal histamine shows diurnal rhythms in rodents and plays a major role in the maintenance of vigilance. No data are available on its diurnal fluctuation in humans, either in health or in neurodegenerative disorders such as Parkinson disease (PD), Alzheimer disease (AD), or Hunt...

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Detalhes bibliográficos
Main Authors: Shan, Ling, Hofman, Michel A., van Wamelen, Daniel J., Van Someren, Eus J.W., Bao, Ai-Min, Swaab Dick, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2012
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Short Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321431/
https://ncbi.nlm.nih.gov/pubmed/22547898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.1838
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