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Targeting stroma to treat cancers

All cancers depend on stroma for support of growth. Leukemias, solid tumors, cancer cells causing effusions, metastases as well as micro-disseminated cancer cells release factors that stimulate stromal cells, which in turn produce ligands that stimulate cancer cells. Therefore, elimination of stroma...

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Main Authors: Engels, Boris, Rowley, Donald A., Schreiber, Hans
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321387/
https://ncbi.nlm.nih.gov/pubmed/22212863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2011.12.008
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