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Toluene Diisocyanate Reactivity with Glutathione Across a Vapor/Liquid Interface and Subsequent Transcarbamoylation of Human Albumin

Glutathione has previously been identified as a reaction target for toluene diisocyanate (TDI) in vitro and in vivo, and has been suggested to contribute to toxic and allergic reactions to exposure. In this study, the reactivity of reduced glutathione (GSH) with TDI in vitro was further investigated...

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Detalhes bibliográficos
Main Authors: Wisnewski, Adam V, Hettick, Justin M., Siegel, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321232/
https://ncbi.nlm.nih.gov/pubmed/21806041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2002433
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