Cholesterol loss during glutamate-mediated excitotoxicity

The deregulation of brain cholesterol metabolism is typical in acute neuronal injury (such as stroke, brain trauma and epileptic seizures) and chronic neurodegenerative diseases (Alzheimer's disease). Since both conditions are characterized by excessive stimulation of glutamate receptors, we ha...

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Detalhes bibliográficos
Main Authors: Sodero, Alejandro O, Vriens, Joris, Ghosh, Debapriya, Stegner, David, Brachet, Anna, Pallotto, Marta, Sassoè-Pognetto, Marco, Brouwers, Jos F, Helms, J Bernd, Nieswandt, Bernhard, Voets, Thomas, Dotti, Carlos G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321209/
https://ncbi.nlm.nih.gov/pubmed/22343944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.31
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