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Structural insights into initial and intermediate steps of the ribosome-recycling process

The ribosome-recycling factor (RRF) and elongation factor-G (EF-G) disassemble the 70S post-termination complex (PoTC) into mRNA, tRNA, and two ribosomal subunits. We have determined cryo-electron microscopic structures of the PoTC·RRF complex, with and without EF-G. We find that domain II of RRF in...

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Detalhes bibliográficos
Main Authors: Yokoyama, Takeshi, Shaikh, Tanvir R, Iwakura, Nobuhiro, Kaji, Hideko, Kaji, Akira, Agrawal, Rajendra K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321202/
https://ncbi.nlm.nih.gov/pubmed/22388519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.22
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