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IAPs limit activation of RIP kinases by TNF receptor 1 during development

Inhibitor of apoptosis (IAP) proteins cIAP1, cIAP2, and XIAP (X-linked IAP) regulate apoptosis and cytokine receptor signalling, but their overlapping functions make it difficult to distinguish their individual roles. To do so, we deleted the genes for IAPs separately and in combination. While lack...

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Main Authors: Moulin, Maryline, Anderton, Holly, Voss, Anne K, Thomas, Tim, Wong, Wendy Wei-Lynn, Bankovacki, Aleksandra, Feltham, Rebecca, Chau, Diep, Cook, Wendy D, Silke, John, Vaux, David L
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321198/
https://ncbi.nlm.nih.gov/pubmed/22327219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.18
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