IAPs limit activation of RIP kinases by TNF receptor 1 during development

Inhibitor of apoptosis (IAP) proteins cIAP1, cIAP2, and XIAP (X-linked IAP) regulate apoptosis and cytokine receptor signalling, but their overlapping functions make it difficult to distinguish their individual roles. To do so, we deleted the genes for IAPs separately and in combination. While lack...

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Detalhes bibliográficos
Main Authors: Moulin, Maryline, Anderton, Holly, Voss, Anne K, Thomas, Tim, Wong, Wendy Wei-Lynn, Bankovacki, Aleksandra, Feltham, Rebecca, Chau, Diep, Cook, Wendy D, Silke, John, Vaux, David L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321198/
https://ncbi.nlm.nih.gov/pubmed/22327219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.18
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