IAPs limit activation of RIP kinases by TNF receptor 1 during development

Inhibitor of apoptosis (IAP) proteins cIAP1, cIAP2, and XIAP (X-linked IAP) regulate apoptosis and cytokine receptor signalling, but their overlapping functions make it difficult to distinguish their individual roles. To do so, we deleted the genes for IAPs separately and in combination. While lack...

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Bibliografiska uppgifter
Huvudupphovsmän: Moulin, Maryline, Anderton, Holly, Voss, Anne K, Thomas, Tim, Wong, Wendy Wei-Lynn, Bankovacki, Aleksandra, Feltham, Rebecca, Chau, Diep, Cook, Wendy D, Silke, John, Vaux, David L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321198/
https://ncbi.nlm.nih.gov/pubmed/22327219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.18
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