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Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor
The THO complex is a key factor in co-transcriptional formation of export-competent messenger ribonucleoprotein particles, yet its structure and mechanism of chromatin recruitment remain unknown. In yeast, this complex has been described as a heterotetramer (Tho2, Hpr1, Mft1, and Thp2) that interact...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321177/ https://ncbi.nlm.nih.gov/pubmed/22314234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.10 |
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