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Tho1, a Novel hnRNP, and Sub2 Provide Alternative Pathways for mRNP Biogenesis in Yeast THO Mutants

THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) were identified as multicopy suppressors of the expression defects of the hpr1Δ mutant of THO. Here we show that multicopy THO1 suppresses the mRNA accumulation and export defe...

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Detalhes bibliográficos
Main Authors: Jimeno, Sonia, Luna, Rosa, García-Rubio, María, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489133/
https://ncbi.nlm.nih.gov/pubmed/16738307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00234-06
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