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Tho1, a Novel hnRNP, and Sub2 Provide Alternative Pathways for mRNP Biogenesis in Yeast THO Mutants

THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) were identified as multicopy suppressors of the expression defects of the hpr1Δ mutant of THO. Here we show that multicopy THO1 suppresses the mRNA accumulation and export defe...

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Bibliographic Details
Main Authors: Jimeno, Sonia, Luna, Rosa, García-Rubio, María, Aguilera, Andrés
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489133/
https://ncbi.nlm.nih.gov/pubmed/16738307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00234-06
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