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An hpr1 Point Mutation That Impairs Transcription and mRNP Biogenesis without Increasing Recombination
THO/TREX, a conserved eukaryotic protein complex, is a key player at the interface between transcription and mRNP metabolism. The lack of a functional THO complex impairs transcription, leads to transcription-dependent hyperrecombination, causes mRNA export defects and fast mRNA decay, and retards r...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636866/ https://ncbi.nlm.nih.gov/pubmed/16908536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00684-06 |
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