Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin

The transcription factor Eomesodermin (Eomes) is involved in early embryonic patterning, but the range of cell fates that it controls as well as its mechanisms of action remain unclear. Here we show that transient expression of Eomes promotes cardiovascular fate during embryonic stem cell differenti...

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Detalhes bibliográficos
Main Authors: van den Ameele, Jelle, Tiberi, Luca, Bondue, Antoine, Paulissen, Catherine, Herpoel, Adèle, Iacovino, Michelina, Kyba, Michael, Blanpain, Cédric, Vanderhaeghen, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321156/
https://ncbi.nlm.nih.gov/pubmed/22402664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.23
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