Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin

The transcription factor Eomesodermin (Eomes) is involved in early embryonic patterning, but the range of cell fates that it controls as well as its mechanisms of action remain unclear. Here we show that transient expression of Eomes promotes cardiovascular fate during embryonic stem cell differenti...

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Autors principals: van den Ameele, Jelle, Tiberi, Luca, Bondue, Antoine, Paulissen, Catherine, Herpoel, Adèle, Iacovino, Michelina, Kyba, Michael, Blanpain, Cédric, Vanderhaeghen, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Scientific Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321156/
https://ncbi.nlm.nih.gov/pubmed/22402664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.23
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