Systems approach identifies HIPK2 as a critical regulator of kidney fibrosis

Kidney fibrosis is a common process that leads to the progression of kidney diseases. We used an integrated computational/experimental systems biology approach to identify upstream protein kinases that regulate gene expression changes in kidneys of HIV-1 transgenic mice (Tg26), which have both tubul...

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Bibliografiske detaljer
Main Authors: Jin, Yuanmeng, Ratnam, Krishna, Chuang, Peter Y., Fan, Ying, Zhong, Yifei, Dai, Yan, Mazloom, Amin, Chen, Edward Y., D'Agati, Vivette, Xiong, Huabao, Ross, Michael, Chen, Nan, Ma'ayan, Avi, He, John Cijiang
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321097/
https://ncbi.nlm.nih.gov/pubmed/22406746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2685
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