Tubular HIPK2 is a key contributor to renal fibrosis

We previously used global Hipk2-null mice in various models of kidney disease to demonstrate the central role of homeodomain-interacting protein kinase 2 (HIPK2) in renal fibrosis development. However, renal tubular epithelial cell–specific (RTEC-specific) HIPK2 function in renal fibrogenesis has ye...

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Udgivet i:JCI Insight
Main Authors: Xiao, Wenzhen, E, Jing, Bao, Li, Fan, Ying, Jin, Yuanmeng, Wang, Andrew, Bauman, David, Li, Zhengzhe, Zheng, Ya-Li, Liu, Ruijie, Lee, Kyung, He, John Cijiang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526443/
https://ncbi.nlm.nih.gov/pubmed/32701510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136004
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