Wild type microglia arrest pathology in a mouse model of Rett syndrome

Rett syndrome is an X-linked autism spectrum disorder. The disease is characterized in the majority of cases by mutation of the MECP2 gene, which encodes a methyl-CpG-binding protein (1–5). Although MeCP2 is expressed in many tissues, the disease is generally attributed to a primary neuronal dysfunc...

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Bibliographic Details
Main Authors: Derecki, Noël C., Cronk, James C., Lu, Zhenjie, Xu, Eric, Abbott, Stephen B. G., Guyenet, Patrice G., Kipnis, Jonathan
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321067/
https://ncbi.nlm.nih.gov/pubmed/22425995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10907
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