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Anti-oncogenic MicroRNA-203 Induces Senescence by Targeting E2F3 Protein in Human Melanoma Cells

MicroRNAs regulate gene expression by repressing translation or directing sequence-specific degradation of their complementary mRNA. We recently reported that miR-203 is down-regulated, and its exogenous expression inhibits cell growth in canine oral malignant melanoma tissue specimens as well as in...

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Detalhes bibliográficos
Main Authors: Noguchi, Shunsuke, Mori, Takashi, Otsuka, Yusami, Yamada, Nami, Yasui, Yuki, Iwasaki, Junya, Kumazaki, Minami, Maruo, Kohji, Akao, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320925/
https://ncbi.nlm.nih.gov/pubmed/22354972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325027
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