Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

Emerging studies on tumor cell-derived extracellular vesicles (EVs) have shown the biological significance in tumor development and microenvironment through reprogramming immune cells around cancer cells. In this study, we used colorectal cancer cells as EVs donor, and T cells as recipients to exami...

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Vydáno v:Oncotarget
Hlavní autoři: Yamada, Nami, Kuranaga, Yuki, Kumazaki, Minami, Shinohara, Haruka, Taniguchi, Kohei, Akao, Yukihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053630/
https://ncbi.nlm.nih.gov/pubmed/27081032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7041
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