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Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

Emerging studies on tumor cell-derived extracellular vesicles (EVs) have shown the biological significance in tumor development and microenvironment through reprogramming immune cells around cancer cells. In this study, we used colorectal cancer cells as EVs donor, and T cells as recipients to exami...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Yamada, Nami, Kuranaga, Yuki, Kumazaki, Minami, Shinohara, Haruka, Taniguchi, Kohei, Akao, Yukihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053630/
https://ncbi.nlm.nih.gov/pubmed/27081032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7041
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