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Wnt/β-Catenin Signaling Regulates Yes-associated Protein (YAP) Gene Expression in Colorectal Carcinoma Cells

Mutations in the Wnt/β-catenin pathway occur in most colorectal cancers (CRCs), and these mutations lead to increased nuclear accumulation of the β-catenin transcriptional co-activator. In the nucleus, β-catenin associates with TCF/LEF sequence specific transcription factors to activate target gene...

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Detalhes bibliográficos
Main Authors: Konsavage, Wesley M., Kyler, Sydney L., Rennoll, Sherri A., Jin, Ge, Yochum, Gregory S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320921/
https://ncbi.nlm.nih.gov/pubmed/22337891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.327767
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