Endoplasmic Reticulum Stress Controls M2 Macrophage Differentiation and Foam Cell Formation

Macrophages are essential in atherosclerosis progression, but regulation of the M1 versus M2 phenotype and their role in cholesterol deposition are unclear. We demonstrate that endoplasmic reticulum (ER) stress is a key regulator of macrophage differentiation and cholesterol deposition. Macrophages...

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Autors principals: Oh, Jisu, Riek, Amy E., Weng, Sherry, Petty, Marvin, Kim, David, Colonna, Marco, Cella, Marina, Bernal-Mizrachi, Carlos
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320912/
https://ncbi.nlm.nih.gov/pubmed/22356914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338673
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