Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

A microscopic method was developed to study the role of platelets in fibrin formation. Perfusion of adhered platelets with plasma under coagulating conditions at a low shear rate (250(−1)) resulted in the assembly of a star-like fibrin network at the platelet surface. The focal fibrin formation on p...

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Bibliografiske detaljer
Main Authors: Cosemans, Judith M. E. M., Schols, Saskia E. M., Stefanini, Lucia, de Witt, Susanne, Feijge, Marion A. H., Hamulyák, Karly, Deckmyn, Hans, Bergmeier, Wolfgang, Heemskerk, Johan W. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320850/
https://ncbi.nlm.nih.gov/pubmed/21037087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-262683
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