Requirements for noncovalent binding of vaccinia topoisomerase I to duplex DNA.
Vaccinia DNA topoisomerase binds duplex DNA and forms a covalent adduct at sites containing a conserved sequence element 5'(C/T)CCTT decreases in the scissile strand. Distinctive aspects of noncovalent versus covalent interaction emerge from analysis of the binding properties of Topo(Phe-274), a mut...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1994
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5360 |
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