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Requirements for noncovalent binding of vaccinia topoisomerase I to duplex DNA.

Vaccinia DNA topoisomerase binds duplex DNA and forms a covalent adduct at sites containing a conserved sequence element 5'(C/T)CCTT decreases in the scissile strand. Distinctive aspects of noncovalent versus covalent interaction emerge from analysis of the binding properties of Topo(Phe-274),...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sekiguchi, J, Shuman, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC332083/
https://ncbi.nlm.nih.gov/pubmed/7816626
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