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Requirements for noncovalent binding of vaccinia topoisomerase I to duplex DNA.

Vaccinia DNA topoisomerase binds duplex DNA and forms a covalent adduct at sites containing a conserved sequence element 5'(C/T)CCTT decreases in the scissile strand. Distinctive aspects of noncovalent versus covalent interaction emerge from analysis of the binding properties of Topo(Phe-274), a mut...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Sekiguchi, J, Shuman, S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1994
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5360
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