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Normalization of Notch upregulation reverts large vessels to microvessels via EphB4-mediated venous reprogramming
High-flow through abnormal blood vessels underlies many life-threatening diseases. The ability to safely and non-invasively normalize these vessels by molecular intervention holds promise to treat these devastating conditions. Here we studied high-flow AV shunts caused by upregulation of Notch signa...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320799/ https://ncbi.nlm.nih.gov/pubmed/22261032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002670 |
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