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Normalization of Notch upregulation reverts large vessels to microvessels via EphB4-mediated venous reprogramming
High-flow through abnormal blood vessels underlies many life-threatening diseases. The ability to safely and non-invasively normalize these vessels by molecular intervention holds promise to treat these devastating conditions. Here we studied high-flow AV shunts caused by upregulation of Notch signa...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320799/ https://ncbi.nlm.nih.gov/pubmed/22261032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002670 |
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