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The influence of imperfectly paired helices I and III on the catalytic activity of hammerhead ribozymes.

Several catalytic antisense RNAs directed against different regions of the genomic or antigenomic RNA of Sendai virus were constructed. All RNAs contained the same catalytic domain based on hammerhead ribozymes but some had deletions or mutations resulting in imperfect helices I and III. Pre-anneale...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zoumadakis, M, Neubert, W J, Tabler, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC332071/
https://ncbi.nlm.nih.gov/pubmed/7816616
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