Direct toxicity of nonsteroidal antiinflammatory drugs for renal medullary cells

Antipyretic analgesics, taken in large doses over a prolonged period, cause a specific form of kidney disease, characterized by papillary necrosis and interstitial scarring. Epidemiological evidence incriminated mixtures of drugs including aspirin (ASA), phenacetin, and caffeine. The mechanism of to...

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Bibliografiske detaljer
Main Authors: Rocha, Gerson M., Michea, Luis F., Peters, Eugenia M., Kirby, Martha, Xu, Yuhui, Ferguson, Douglas R., Burg, Maurice B.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC33207/
https://ncbi.nlm.nih.gov/pubmed/11320259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091057698
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