Direct toxicity of nonsteroidal antiinflammatory drugs for renal medullary cells

Antipyretic analgesics, taken in large doses over a prolonged period, cause a specific form of kidney disease, characterized by papillary necrosis and interstitial scarring. Epidemiological evidence incriminated mixtures of drugs including aspirin (ASA), phenacetin, and caffeine. The mechanism of to...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Rocha, Gerson M., Michea, Luis F., Peters, Eugenia M., Kirby, Martha, Xu, Yuhui, Ferguson, Douglas R., Burg, Maurice B.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2001
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11320259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.091057698
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