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Modified RNA sequence pools for in vitro selection.
We report the use of modified RNA, in which the 2'-OH group of pyrimidines is replaced by a 2'-amino (2'-NH2) group to identify high affinity ligands specific for human neutrophil elastase (HNE) by in vitro selection. Compared to unmodified RNA the 2'-NH2-modified RNA ligands sho...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1994
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC332065/ https://ncbi.nlm.nih.gov/pubmed/7529404 |
| Tagit: |
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