Modified RNA sequence pools for in vitro selection.
We report the use of modified RNA, in which the 2'-OH group of pyrimidines is replaced by a 2'-amino (2'-NH2) group to identify high affinity ligands specific for human neutrophil elastase (HNE) by in vitro selection. Compared to unmodified RNA the 2'-NH2-modified RNA ligands show enhanced stability...
Na minha lista:
| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1994
|
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7529404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5229 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|