Alignment-Free Design of Highly Discriminatory Diagnostic Primer Sets for Escherichia coli O104:H4 Outbreak Strains

BACKGROUND: An Escherichia coli O104:H4 outbreak in Germany in summer 2011 caused 53 deaths, over 4000 individual infections across Europe, and considerable economic, social and political impact. This outbreak was the first in a position to exploit rapid, benchtop high-throughput sequencing (HTS) te...

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Autori principali: Pritchard, Leighton, Holden, Nicola J., Bielaszewska, Martina, Karch, Helge, Toth, Ian K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320637/
https://ncbi.nlm.nih.gov/pubmed/22496820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034498
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