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Phosphorylation of the c-Fos and c-Jun HOB1 motif stimulates its activation capacity.

The c-Fos and c-Jun proteins bind an AP1 site and activate transcription synergistically. These two proteins have a common activation domain which has two co-operating motifs, HOB1 and HOB2. The HOB1 motif of c-Jun includes S73 which is required for Ha-Ras-induced super-activation and phosphorylatio...

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Bibliografiske detaljer
Main Authors: Bannister, A J, Brown, H J, Sutherland, J A, Kouzarides, T
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC332056/
https://ncbi.nlm.nih.gov/pubmed/7816602
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