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Phosphorylation of the c-Fos and c-Jun HOB1 motif stimulates its activation capacity.
The c-Fos and c-Jun proteins bind an AP1 site and activate transcription synergistically. These two proteins have a common activation domain which has two co-operating motifs, HOB1 and HOB2. The HOB1 motif of c-Jun includes S73 which is required for Ha-Ras-induced super-activation and phosphorylatio...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1994
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332056/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5173 |
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