ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics

BACKGROUND: Colorectal (CRC) carcinogenesis through various morphological stages has been linked to several genetic and epigenetic changes. The Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates. METHODS: In this study, we investigated the presence...

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Detalhes bibliográficos
Main Authors: Levidou, Georgia, Saetta, Angelica A, Gigelou, Fanie, Karlou , Maria, Papanastasiou, Polyanthi, Stamatelli, Angeliki, Kavantzas, Nikolaos, Michalopoulos, Nikolaos V, Agrogiannis, George, Patsouris, Efstratios, Korkolopoulou, Penelope
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320554/
https://ncbi.nlm.nih.gov/pubmed/22376079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-10-47
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