ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics

<p>Abstract</p> <p>Background</p> <p>Colorectal (CRC) carcinogenesis through various morphological stages has been linked to several genetic and epigenetic changes. The Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates...

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Hauptverfasser: Levidou Georgia, Saetta Angelica A, Gigelou Fanie, Karlou Maria, Papanastasiou Polyanthi, Stamatelli Angeliki, Kavantzas Nikolaos, Michalopoulos Nikolaos V, Agrogiannis George, Patsouris Efstratios, Korkolopoulou Penelope
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2012-02-01
Schriftenreihe:World Journal of Surgical Oncology
Online Zugang:http://www.wjso.com/content/10/1/47
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