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Alcohol Suppresses the Granulopoietic Response to Pulmonary S. Pneumoniae Infection with Enhancement of STAT3 Signaling()
Enhanced granulopoietic activity is crucial for host defense against bacterial pneumonia. Alcohol impairs this response. The underlying mechanisms remain obscure. Granulocyte colony-stimulating factor (G-CSF) produced by infected lung tissue plays a key role in stimulating bone marrow granulopoiesis...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319982/ https://ncbi.nlm.nih.gov/pubmed/21357267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002885 |
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