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Alcohol Impairs the Myeloid Proliferative Response to Bacteremia in Mice via Inhibiting the Stem Cell Antigen-1 - Extracellular-Regulated Kinase Pathway(1)

Enhancement of stem cell antigen-1 (Sca-1) expression by myeloid precursors promotes the granulopoietic response to bacterial infection. However, the underlying mechanisms remain unclear. Extracellular-regulated kinase (ERK) pathway activation strongly enhances proliferation of hematopoietic progeni...

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Bibliographic Details
Main Authors: Melvan, John Nicholas, Siggins, Robert W., Stanford, William L., Porretta, Connie, Nelson, Steve, Bagby, Gregory J., Zhang, Ping
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782293/
https://ncbi.nlm.nih.gov/pubmed/22238460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102395
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