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REPROGRAMMING TUMOR-ASSOCIATED DENDRITIC CELLS IN VIVO USING MICRORNA MIMETICS TRIGGERS PROTECTIVE IMMUNITY AGAINST OVARIAN CANCER

Modulating the activity of microRNAs (miRNAs) provides opportunities for novel cancer interventions. However, low bioavailability and poor cellular uptake are major challenges for delivering miRNA mimetics specifically to tumor cells. Here, we took advantage of the spontaneous enhanced endocytic act...

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Hlavní autoři: Cubillos-Ruiz, Juan R., Baird, Jason R., Tesone, Amelia J., Rutkowski, Melanie R., Scarlett, Uciane K., Camposeco-Jacobs, Ana L., Anadon-Arnillas, Jorge, Harwood, Noah M., Korc, Murray, Fiering, Steven N., Sempere, Lorenzo F., Conejo-Garcia, Jose R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319850/
https://ncbi.nlm.nih.gov/pubmed/22307839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3160
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