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Cancer vaccination drives Nanog-dependent evolution of tumor cells towards an immune-resistant and stem-like phenotype

Due to the exquisite specificity and potency of the immune system, vaccination is in theory the most precise and powerful approach for controlling cancer. However, current data from clinical trials indicate that vaccination rarely yields significant benefits for cancer patients in terms of tumor pro...

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Detalhes bibliográficos
Main Authors: Noh, Kyung Hee, Lee, Young-Ho, Jeon, Ju-Hong, Kang, Tae Heung, Mao, Chih-Ping, Wu, T-C, Kim, Tae Woo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319841/
https://ncbi.nlm.nih.gov/pubmed/22337995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3758
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