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Cancer vaccination drives Nanog-dependent evolution of tumor cells towards an immune-resistant and stem-like phenotype

Due to the exquisite specificity and potency of the immune system, vaccination is in theory the most precise and powerful approach for controlling cancer. However, current data from clinical trials indicate that vaccination rarely yields significant benefits for cancer patients in terms of tumor pro...

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Bibliographic Details
Main Authors: Noh, Kyung Hee, Lee, Young-Ho, Jeon, Ju-Hong, Kang, Tae Heung, Mao, Chih-Ping, Wu, T-C, Kim, Tae Woo
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319841/
https://ncbi.nlm.nih.gov/pubmed/22337995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3758
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