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Potent synergistic effect of IL-3 and TNF on matrix metalloproteinase 9 generation by human eosinophils

TNF (designated as TNF-α under previous nomenclature) is the preeminent activator of MMP-9 generation from a variety of cells including eosinophils. We have previously established that TNF strongly synergizes with IFN-γ and IL-4 for eosinophil synthesis of Th1- and Th2-type chemokines respectively....

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Detalhes bibliográficos
Main Authors: Kelly, Elizabeth A. B., Liu, Lin Ying, Esnault, Stephane, Johnson, Beatriz Helena Quinchia, Jarjour, Nizar N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319644/
https://ncbi.nlm.nih.gov/pubmed/22321809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2012.01.009
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