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Proteomic and Phospho-proteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL-3

Purified human eosinophils treated for 18-24 h with IL-3 adopt a unique activated phenotype marked by increased reactivity to aggregated immunoglobulin-G (IgG). To characterize this phenotype, we quantified protein abundance and phosphorylation by multi-plexed isobaric labeling combined with high-re...

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Veröffentlicht in:J Proteome Res
Hauptverfasser: Esnault, Stephane, Hebert, Alexander S, Jarjour, Nizar N, Coon, Joshua J, Mosher, Deane F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984179/
https://ncbi.nlm.nih.gov/pubmed/29706072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00057
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