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Macrophage-Associated Mesenchymal Stem Cells Assume an Activated, Migratory, Pro-Inflammatory Phenotype with Increased IL-6 and CXCL10 Secretion

Mesenchymal stem cells (MSCs) exhibit tropism for sites of tissue injury and tumors. However, the influence of the microenvironment on MSC phenotype and localization remains incompletely characterized. In this study, we begin to define a macrophage-induced MSC phenotype. These MSCs secrete interleuk...

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Detalhes bibliográficos
Main Authors: Anton, Kevin, Banerjee, Debabrata, Glod, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319627/
https://ncbi.nlm.nih.gov/pubmed/22496888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035036
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